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Enzymatic Transition States, Transition-State Analogs, Dynamics, Thermodynamics, and Lifetimes

Experimental analysis of enzymatic transition-state structures uses kinetic isotope effects (KIEs) to report on bonding and geometry differences between reactants and the transition state. Computational correlation of experimental values with chemical models permits three-dimensional geometric and e...

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Detalhes bibliográficos
Publicado no:Annu Rev Biochem
Autor principal: Schramm, Vern L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502542/
https://ncbi.nlm.nih.gov/pubmed/21675920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biochem-061809-100742
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