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Transition state structure of human 5′-methylthioadenosine phosphorylase
Kinetic isotope effects (KIEs) and computer modeling using density functional theory were used to approximate the transition state of human 5′-methylthioadenosine phosphorylase (MTAP). KIEs were measured on the arsenolysis of 5′-methylthioadenosine (MTA) catalyzed by MTAP and were corrected for the...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2522318/ https://ncbi.nlm.nih.gov/pubmed/17090056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja065419p |
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