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Transition state structure of human 5′-methylthioadenosine phosphorylase

Kinetic isotope effects (KIEs) and computer modeling using density functional theory were used to approximate the transition state of human 5′-methylthioadenosine phosphorylase (MTAP). KIEs were measured on the arsenolysis of 5′-methylthioadenosine (MTA) catalyzed by MTAP and were corrected for the...

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Detaylı Bibliyografya
Asıl Yazarlar: Singh, Vipender, Schramm, Vern L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2522318/
https://ncbi.nlm.nih.gov/pubmed/17090056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja065419p
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