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Methylthioadenosine Deaminase in an Alternative Quorum Sensing Pathway in Pseudomonas aeruginosa

Pseudomonas aeruginosa possesses an unusual pathway for 5′-methylthioadenosine (MTA) metabolism involving deamination to 5′-methylthioinosine (MTI) followed by N-ribosyl phosphorolysis to hypoxanthine and 5-methylthio-α-D-ribose 1-phosphate. The specific MTI phosphorylase of P. aeruginosa has been r...

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Detalhes bibliográficos
Main Authors: Guan, Rong, Ho, Meng-Chiao, Frohlich, Richard F.G., Tyler, Peter C., Almo, Steven C., Schramm, Vern L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567251/
https://ncbi.nlm.nih.gov/pubmed/23050701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301062y
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