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Salmonella enterica MTAN at 1.36 Å resolution. Structure-based design of new transition state analogues

Accumulation of 5′-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) in bacteria disrupts the S-adenosylmethionine pool to alter biological methylations, synthesis of polyamines and production of quorum sensing molecules. Bacterial metabolism of MTA and SAH depends on MTA/SAH nucleosidase (...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Haapalainen, Antti M., Thomas, Keisha, Tyler, Peter C., Evans, Gary B., Almo, Steven C., Schramm, Vern L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690532/
https://ncbi.nlm.nih.gov/pubmed/23685211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.04.009
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