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Transition State Analogues Rescue Ribosomes from Saporin-L1 Ribosome Inactivating Protein
Ribosome-inactivating proteins (RIPs) catalyze the hydrolytic depurination of one or more adenosine residues from eukaryotic ribosomes. Depurination of the ribosomal sarcin-ricin tetraloop (GAGA) causes inhibition of protein synthesis and cellular death. We characterized the catalytic properties of...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2762729/ https://ncbi.nlm.nih.gov/pubmed/19764816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901425h |
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