Reversal of Neurological Defects in a Mouse Model of Rett Syndrome

Por Guy, Jacky, Gan, Jian, Selfridge, Jim, Cobb, Stuart, Bird, Adrian
Publicado no Science (2007)

Correction of liver dysfunction in DNA repair-deficient mice with an ERCC1 transgene

Por Selfridge, Jim, Hsia, Kan-Tai, Redhead, Nicola J., Melton, David W.
Publicado em 2001

Postnatal inactivation reveals enhanced requirement for MeCP2 at distinct age windows

Por Cheval, Hélène, Guy, Jacky, Merusi, Cara, De Sousa, Dina, Selfridge, Jim, Bird, Adrian
Publicado em 2012

Base Excision by Thymine DNA Glycosylase Mediates DNA-Directed Cytotoxicity of 5-Fluorouracil

Por Kunz, Christophe, Focke, Frauke, Saito, Yusuke, Schuermann, David, Lettieri, Teresa, Selfridge, Jim, Schär, Primo
Publicado em 2009

Deletion of Genes Implicated in Protecting the Integrity of Male Germ Cells Has Differential Effects on the Incidence of DNA Breaks and Germ Cell Loss

Por Paul, Catriona, Povey, Joanne E., Lawrence, Nicola J., Selfridge, Jim, Melton, David W., Saunders, Philippa T. K.
Publicado em 2007

A mutation-led search for novel functional domains in MeCP2

Por Guy, Jacky, Alexander-Howden, Beatrice, FitzPatrick, Laura, DeSousa, Dina, Koerner, Martha V, Selfridge, Jim, Bird, Adrian
Publicado no Hum Mol Genet (2018)

Affinity for DNA Contributes to NLS Independent Nuclear Localization of MeCP2

Por Lyst, Matthew J., Ekiert, Robert, Guy, Jacky, Selfridge, Jim, Koerner, Martha V., Merusi, Cara, De Sousa, Dina, Bird, Adrian
Publicado no Cell Rep (2018)

The molecular basis of variable phenotypic severity among common missense mutations causing Rett syndrome

Por Brown, Kyla, Selfridge, Jim, Lagger, Sabine, Connelly, John, De Sousa, Dina, Kerr, Alastair, Webb, Shaun, Guy, Jacky, Merusi, Cara, Koerner, Martha V., Bird, Adrian
Publicado no Hum Mol Genet (2016)

Radically truncated MeCP2 rescues Rett syndrome-like neurological defects

Por Tillotson, Rebekah, Selfridge, Jim, Koerner, Martha V., Gadalla, Kamal K. E., Guy, Jacky, De Sousa, Dina, Hector, Ralph D., Cobb, Stuart R., Bird, Adrian
Publicado no Nature (2017)

Morphological and functional reversal of phenotypes in a mouse model of Rett syndrome

Por Robinson, Lianne, Guy, Jacky, McKay, Leanne, Brockett, Emma, Spike, Rosemary C., Selfridge, Jim, De Sousa, Dina, Merusi, Cara, Riedel, Gernot, Bird, Adrian, Cobb, Stuart R.
Publicado em 2012

Toxicity of overexpressed MeCP2 is independent of HDAC3 activity

Por Koerner, Martha V., FitzPatrick, Laura, Selfridge, Jim, Guy, Jacky, De Sousa, Dina, Tillotson, Rebekah, Kerr, Alastair, Sun, Zheng, Lazar, Mitchell A., Lyst, Matthew J., Bird, Adrian
Publicado no Genes Dev (2018)

Male Infertility and DNA Damage in Doppel Knockout and Prion Protein/Doppel Double-Knockout Mice

Por Paisley, Derek, Banks, Stephen, Selfridge, Jim, McLennan, Neil F., Ritchie, Ann-Marie, McEwan, Carolanne, Irvine, D. Stewart, Saunders, Philippa T. K., Manson, Jean C., Melton, David W.
Publicado em 2004

MeCP2 recognizes cytosine methylated tri-nucleotide and di-nucleotide sequences to tune transcription in the mammalian brain

Por Lagger, Sabine, Connelly, John C., Schweikert, Gabriele, Webb, Shaun, Selfridge, Jim, Ramsahoye, Bernard H., Yu, Miao, He, Chuan, Sanguinetti, Guido, Sowers, Lawrence C., Walkinshaw, Malcolm D., Bird, Adrian
Publicado no PLoS Genet (2017)

CpG islands influence chromatin structure via the CpG-binding protein Cfp1

Por Thomson, John P., Skene, Peter J., Selfridge, Jim, Clouaire, Thomas, Guy, Jacky, Webb, Shaun, Kerr, Alastair R. W., Deaton, Aimée, Andrews, Rob, James, Keith D., Turner, Daniel J., Illingworth, Robert, Bird, Adrian
Publicado em 2010

SALL4 controls cell fate in response to DNA base composition

Por Pantier, Raphaël, Chhatbar, Kashyap, Quante, Timo, Skourti-Stathaki, Konstantina, Cholewa-Waclaw, Justyna, Alston, Grace, Alexander-Howden, Beatrice, Lee, Heng Yang, Cook, Atlanta G., Spruijt, Cornelia G., Vermeulen, Michiel, Selfridge, Jim, Bird, Adrian
Publicado no Mol Cell (2021)

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor

Por Lyst, Matthew J, Ekiert, Robert, Ebert, Daniel H, Merusi, Cara, Nowak, Jakub, Selfridge, Jim, Guy, Jacky, Kastan, Nathaniel R, Robinson, Nathaniel D, de Lima Alves, Flavia, Rappsilber, Juri, Greenberg, Michael E, Bird, Adrian
Publicado em 2013

Exclusive expression of MeCP2 in the nervous system distinguishes between brain and peripheral Rett syndrome-like phenotypes

Por Ross, Paul D., Guy, Jacky, Selfridge, Jim, Kamal, Bushra, Bahey, Noha, Tanner, K. Elizabeth, Gillingwater, Thomas H., Jones, Ross A., Loughrey, Christopher M., McCarroll, Charlotte S., Bailey, Mark E.S., Bird, Adrian, Cobb, Stuart
Publicado no Hum Mol Genet (2016)

An Orphan CpG Island Drives Expression of a let-7 miRNA Precursor with an Important Role in Mouse Development

Por Koerner, Martha V., Chhatbar, Kashyap, Webb, Shaun, Cholewa-Waclaw, Justyna, Selfridge, Jim, De Sousa, Dina, Skarnes, Bill, Rosen, Barry, Thomas, Mark, Bottomley, Joanna, Ramirez-Solis, Ramiro, Lelliott, Christopher, Adams, David J., Bird, Adrian
Publicado no Epigenomes (2019)

Kaiso-Deficient Mice Show Resistance to Intestinal Cancer

Por Prokhortchouk, Anna, Sansom, Owen, Selfridge, Jim, Caballero, Isabel M., Salozhin, Sergey, Aithozhina, Dana, Cerchietti, Leandro, Meng, Fan Guo, Augenlicht, Leonard H., Mariadason, John M., Hendrich, Brian, Melnick, Ari, Prokhortchouk, Egor, Clarke, Alan, Bird, Adrian
Publicado em 2006

A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog

Por Hagelkruys, Astrid, Lagger, Sabine, Krahmer, Julia, Leopoldi, Alexandra, Artaker, Matthias, Pusch, Oliver, Zezula, Jürgen, Weissmann, Simon, Xie, Yunli, Schöfer, Christian, Schlederer, Michaela, Brosch, Gerald, Matthias, Patrick, Selfridge, Jim, Lassmann, Hans, Knoblich, Jürgen A., Seiser, Christian
Publicado no Development (2014)