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Affinity for DNA Contributes to NLS Independent Nuclear Localization of MeCP2
MeCP2 is a nuclear protein that is mutated in the severe neurological disorder Rett syndrome (RTT). The ability to target β-galactosidase to the nucleus was previously used to identify a conserved nuclear localization signal (NLS) in MeCP2 that interacts with the nuclear import factors KPNA3 and KPN...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6130050/ https://ncbi.nlm.nih.gov/pubmed/30157418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.07.099 |
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