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Sequence‐specific DNA binding by AT‐hook motifs in MeCP2
MeCP2 is a chromatin‐associated protein that is mutated in Rett syndrome. Its methyl‐CpG‐binding domain interacts with DNA containing methylated cytosine, but other modes of recruitment to the genome have also been proposed. Here, we use in vitro and in vivo assays to investigate the DNA binding spe...
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| Publicado no: | FEBS Lett |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5028900/ https://ncbi.nlm.nih.gov/pubmed/27461740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12328 |
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