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Absence of MeCP2 binding to non-methylated GT-rich sequences in vivo
MeCP2 is a nuclear protein that binds to sites of cytosine methylation in the genome. While most evidence confirms this epigenetic mark as the primary determinant of DNA binding, MeCP2 is also reported to have an affinity for non-methylated DNA sequences. Here we investigated the molecular basis and...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7144902/ https://ncbi.nlm.nih.gov/pubmed/32064528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa102 |
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