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Quantitative analysis questions the role of MeCP2 as a global regulator of alternative splicing
MeCP2 is an abundant protein in mature nerve cells, where it binds to DNA sequences containing methylated cytosine. Mutations in the MECP2 gene cause the severe neurological disorder Rett syndrome (RTT), provoking intensive study of the underlying molecular mechanisms. Multiple functions have been p...
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| Publicado no: | PLoS Genet |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7584252/ https://ncbi.nlm.nih.gov/pubmed/33048927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009087 |
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