Impaired in vivo binding of MeCP2 to chromatin in the absence of its DNA methyl-binding domain

MeCP2 is a methyl-CpG-binding protein that is a main component of brain chromatin in vertebrates. In vitro studies have determined that in addition to its specific methyl-CpG-binding domain (MBD) MeCP2 also has several chromatin association domains. However, the specific interactions of MeCP2 with m...

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Hlavní autoři: Stuss, David P., Cheema, Manjinder, Ng, Marlee K., Martinez de Paz, Alexia, Williamson, Brad, Missiaen, Kristal, Cosman, Joel D., McPhee, David, Esteller, Manel, Hendzel, Michael, Delaney, Kerry, Ausió, Juan
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
Gene Regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643609/
https://ncbi.nlm.nih.gov/pubmed/23558747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt213
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