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Sequence‐specific DNA binding by AT‐hook motifs in MeCP2

MeCP2 is a chromatin‐associated protein that is mutated in Rett syndrome. Its methyl‐CpG‐binding domain interacts with DNA containing methylated cytosine, but other modes of recruitment to the genome have also been proposed. Here, we use in vitro and in vivo assays to investigate the DNA binding spe...

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Detalles Bibliográficos
Publicado en:FEBS Lett
Main Authors: Lyst, Matthew J., Connelly, John, Merusi, Cara, Bird, Adrian
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028900/
https://ncbi.nlm.nih.gov/pubmed/27461740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12328
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