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MeCP2 Binding Cooperativity Inhibits DNA Modification-Specific Recognition

Methyl-CpG binding protein 2 (MeCP2) is a multifunctional protein that guides neuronal development through its binding to DNA, recognition of sites of methyl-CpG (mCpG) DNA modification, and interaction with other regulatory proteins. Our study explores the relationship between mCpG and hydroxymethy...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Khrapunov, Sergei, Tao, Yisong, Cheng, Huiyong, Padlan, Camille, Harris, Richard, Galanopoulou, Aristea S., Greally, John M., Girvin, Mark E., Brenowitz, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532394/
https://ncbi.nlm.nih.gov/pubmed/27420643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00451
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