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Postnatal inactivation reveals enhanced requirement for MeCP2 at distinct age windows
Rett Syndrome is a neurological disorder caused by mutations in the X-linked MECP2 gene. Mouse models where Mecp2 is inactivated or mutated recapitulate several features of the disorder and have demonstrated a requirement for the protein to ensure brain function in adult mice. We deleted the Mecp2 g...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3412380/ https://ncbi.nlm.nih.gov/pubmed/22653753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds208 |
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