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Postnatal inactivation reveals enhanced requirement for MeCP2 at distinct age windows

Rett Syndrome is a neurological disorder caused by mutations in the X-linked MECP2 gene. Mouse models where Mecp2 is inactivated or mutated recapitulate several features of the disorder and have demonstrated a requirement for the protein to ensure brain function in adult mice. We deleted the Mecp2 g...

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Autori principali: Cheval, Hélène, Guy, Jacky, Merusi, Cara, De Sousa, Dina, Selfridge, Jim, Bird, Adrian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412380/
https://ncbi.nlm.nih.gov/pubmed/22653753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds208
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