Lanean...
The molecular basis of variable phenotypic severity among common missense mutations causing Rett syndrome
Rett syndrome is caused by mutations in the X-linked MECP2 gene, which encodes a chromosomal protein that binds to methylated DNA. Mouse models mirror the human disorder and therefore allow investigation of phenotypes at a molecular level. We describe an Mecp2 allelic series representing the three m...
Gorde:
| Argitaratua izan da: | Hum Mol Genet |
|---|---|
| Egile Nagusiak: | , , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Oxford University Press
2016
|
| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4731022/ https://ncbi.nlm.nih.gov/pubmed/26647311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv496 |
| Etiketak: |
Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!
|