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Morphological and functional reversal of phenotypes in a mouse model of Rett syndrome

Rett syndrome is a neurological disorder caused by mutation of the X-linked MECP2 gene. Mice lacking functional Mecp2 display a spectrum of Rett syndrome-like signs, including disturbances in motor function and abnormal patterns of breathing, accompanied by structural defects in central motor areas...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Robinson, Lianne, Guy, Jacky, McKay, Leanne, Brockett, Emma, Spike, Rosemary C., Selfridge, Jim, De Sousa, Dina, Merusi, Cara, Riedel, Gernot, Bird, Adrian, Cobb, Stuart R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437019/
https://ncbi.nlm.nih.gov/pubmed/22525157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aws096
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