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Reversal of Neurological Defects in a Mouse Model of Rett Syndrome

Rett Syndrome is an autism spectrum disorder caused by mosaic expression of mutant copies of the X-linked MECP2 gene in neurons. Neuronal death is absent suggesting that this is not a neurodegenerative disorder. An important question for future therapeutic approaches to this and related disorders co...

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Bibliografische gegevens
Gepubliceerd in:Science
Hoofdauteurs: Guy, Jacky, Gan, Jian, Selfridge, Jim, Cobb, Stuart, Bird, Adrian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610836/
https://ncbi.nlm.nih.gov/pubmed/17289941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1138389
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