Metabolomic and Lipidomic Analysis of the Heart of Peroxisome Proliferator-Activated Receptor-γ Coactivator 1-β Knock Out Mice on a High Fat Diet

Por McCombie, Gregor, Medina-Gomez, Gema, Lelliott, Christopher J, Vidal-Puig, Antonio, Griffin, Julian L
Publicado em 2012

Mitochondrial Fusion Is Increased by the Nuclear Coactivator PGC-1β

Por Liesa, Marc, Borda-d'Água, Bárbara, Medina-Gómez, Gema, Lelliott, Christopher J., Paz, José Carlos, Rojo, Manuel, Palacín, Manuel, Vidal-Puig, Antonio, Zorzano, Antonio
Publicado em 2008

High-fat feeding rapidly induces obesity and lipid derangements in C57BL/6N mice

Por Podrini, Christine, Cambridge, Emma L., Lelliott, Christopher J., Carragher, Damian M., Estabel, Jeanne, Gerdin, Anna-Karin, Karp, Natasha A., Scudamore, Cheryl L., Ramirez-Solis, Ramiro, White, Jacqueline K.
Publicado em 2013

ETO/MTG8 Is an Inhibitor of C/EBPβ Activity and a Regulator of Early Adipogenesis

Por Rochford, Justin J., Semple, Robert K., Laudes, Matthias, Boyle, Keith B., Christodoulides, Constantinos, Mulligan, Claire, Lelliott, Christopher J., Schinner, Sven, Hadaschik, Dirk, Mahadevan, Meera, Sethi, Jaswinder K., Vidal-Puig, Antonio, O'Rahilly, Stephen
Publicado em 2004

Peroxisome proliferator-activated receptor-γ coactivator 1-α (PGC1α) is a metabolic regulator of intestinal epithelial cell fate

Por D'Errico, Ilenia, Salvatore, Lorena, Murzilli, Stefania, Lo Sasso, Giuseppe, Latorre, Dominga, Martelli, Nicola, Egorova, Anastasia V., Polishuck, Roman, Madeyski-Bengtson, Katja, Lelliott, Christopher, Vidal-Puig, Antonio J., Seibel, Peter, Villani, Gaetano, Moschetta, Antonio
Publicado em 2011

Characterization of the human, mouse and rat PGC1 beta (peroxisome-proliferator-activated receptor-gamma co-activator 1 beta) gene in vitro and in vivo.

Por Meirhaeghe, Aline, Crowley, Vivion, Lenaghan, Carol, Lelliott, Christopher, Green, Kath, Stewart, Abigail, Hart, Kevin, Schinner, Sven, Sethi, Jaswinder K, Yeo, Giles, Brand, Martin D, Cortright, Ron N, O'Rahilly, Stephen, Montague, Carl, Vidal-Puig, Antonio J
Publicado em 2003

Deletion of the metabolic transcriptional coactivator PGC1β induces cardiac arrhythmia

Por Gurung, Iman S., Medina-Gomez, Gema, Kis, Adrienn, Baker, Michael, Velagapudi, Vidya, Neogi, Sudeshna Guha, Campbell, Mark, Rodriguez-Cuenca, Sergio, Lelliott, Christopher, McFarlane, Ian, Oresic, Matej, Grace, Andrew A., Vidal-Puig, Antonio, Huang, Christopher L.-H.
Publicado em 2011

Monoclonal Antibody Targeting of Fibroblast Growth Factor Receptor 1c Ameliorates Obesity and Glucose Intolerance via Central Mechanisms

Por Lelliott, Christopher J., Ahnmark, Andrea, Admyre, Therese, Ahlstedt, Ingela, Irving, Lorraine, Keyes, Feenagh, Patterson, Laurel, Mumphrey, Michael B., Bjursell, Mikael, Gorman, Tracy, Bohlooly-Y, Mohammad, Buchanan, Andrew, Harrison, Paula, Vaughan, Tristan, Berthoud, Hans-Rudolf, Lindén, Daniel
Publicado no PLoS One (2014)

PGC-1β Deficiency Accelerates the Transition to Heart Failure in Pressure Overload Hypertrophy: PGC-1β and Pressure Overload

Por Riehle, Christian, Wende, Adam R, Zaha, Vlad G, Pires, Karla Maria, Wayment, Benjamin, Olsen, Curtis, Bugger, Heiko, Buchanan, Jonathan, Wang, Xiaohui, Moreira, Annie Bello, Doenst, Torsten, Medina-Gomez, Gema, Litwin, Sheldon E, Lelliott, Christopher J, Vidal-Puig, Antonio, Abel, E. Dale
Publicado em 2011

Targeting of Slc25a21 Is Associated with Orofacial Defects and Otitis Media Due to Disrupted Expression of a Neighbouring Gene

Por Maguire, Simon, Estabel, Jeanne, Ingham, Neil, Pearson, Selina, Ryder, Edward, Carragher, Damian M., Walker, Nicolas, Bussell, James, Chan, Wai-In, Keane, Thomas M., Adams, David J., Scudamore, Cheryl L., Lelliott, Christopher J., Ramírez-Solis, Ramiro, Karp, Natasha A., Steel, Karen P., White, Jacqueline K., Gerdin, Anna-Karin
Publicado em 2014

Alkaline ceramidase 1 is essential for mammalian skin homeostasis and regulating whole‐body energy expenditure

Por Liakath‐Ali, Kifayathullah, Vancollie, Valerie E, Lelliott, Christopher J, Speak, Anneliese O, Lafont, David, Protheroe, Hayley J, Ingvorsen, Camilla, Galli, Antonella, Green, Angela, Gleeson, Diane, Ryder, Ed, Glover, Leanne, Vizcay‐Barrena, Gema, Karp, Natasha A, Arends, Mark J, Brenn, Thomas, Spiegel, Sarah, Adams, David J, Watt, Fiona M, van der Weyden, Louise
Publicado no J Pathol (2016)

Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance

Por López, Miguel, Varela, Luis, Vázquez, María J., Rodríguez-Cuenca, Sergio, González, Carmen R., Velagapudi, Vidya R., Morgan, Donald A., Schoenmakers, Erik, Agassandian, Khristofor, Lage, Ricardo, de Morentin, Pablo Blanco Martínez, Tovar, Sulay, Nogueiras, Rubén, Carling, David, Lelliott, Christopher, Gallego, Rosalía, Orešič, Matej, Chatterjee, Krishna, Saha, Asish K., Rahmouni, Kamal, Diéguez, Carlos, Vidal-Puig, Antonio
Publicado em 2010

The Link Between Nutritional Status and Insulin Sensitivity Is Dependent on the Adipocyte-Specific Peroxisome Proliferator–Activated Receptor-γ2 Isoform

Por Medina-Gomez, Gema, Virtue, Sam, Lelliott, Christopher, Boiani, Romina, Campbell, Mark, Christodoulides, Constantinos, Perrin, Christophe, Jimenez-Linan, Mercedes, Blount, Margaret, Dixon, John, Zahn, Dirk, Thresher, Rosemary R., Aparicio, Sam, Carlton, Mark, Colledge, William H., Kettunen, Mikko I., Seppänen-Laakso, Tuulikki, Sethi, Jaswinder K., O’Rahilly, Stephen, Brindle, Kevin, Cinti, Saverio, Orešič, Matej, Burcelin, Remy, Vidal-Puig, Antonio
Publicado no Diabetes (2005)

Ablation of PGC-1β Results in Defective Mitochondrial Activity, Thermogenesis, Hepatic Function, and Cardiac Performance

Por Lelliott, Christopher J, Medina-Gomez, Gema, Petrovic, Natasa, Kis, Adrienn, Feldmann, Helena M, Bjursell, Mikael, Parker, Nadeene, Curtis, Keira, Campbell, Mark, Hu, Ping, Zhang, Dongfang, Litwin, Sheldon E, Zaha, Vlad G, Fountain, Kimberly T, Boudina, Sihem, Jimenez-Linan, Mercedes, Blount, Margaret, Lopez, Miguel, Meirhaeghe, Aline, Bohlooly-Y, Mohammad, Storlien, Leonard, Strömstedt, Maria, Snaith, Michael, Orešič, Matej, Abel, E. Dale, Cannon, Barbara, Vidal-Puig, Antonio
Publicado em 2006

Adaptive Changes of the Insig1/SREBP1/SCD1 Set Point Help Adipose Tissue to Cope With Increased Storage Demands of Obesity

Por Carobbio, Stefania, Hagen, Rachel M., Lelliott, Christopher J., Slawik, Marc, Medina-Gomez, Gema, Tan, Chong-Yew, Sicard, Audrey, Atherton, Helen J., Barbarroja, Nuria, Bjursell, Mikael, Bohlooly-Y, Mohammad, Virtue, Sam, Tuthill, Antoinette, Lefai, Etienne, Laville, Martine, Wu, Tingting, Considine, Robert V., Vidal, Hubert, Langin, Dominique, Oresic, Matej, Tinahones, Francisco J., Fernandez-Real, Jose Manuel, Griffin, Julian L., Sethi, Jaswinder K., López, Miguel, Vidal-Puig, Antonio
Publicado em 2013