Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance

Thyroid hormones have widespread cellular effects; however it is unclear whether their effects on the central nervous system (CNS) contribute to global energy balance. Here, we demonstrate that either whole body hyperthyroidism or central administration of triiodothyronine (T3) decreases the activit...

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Main Authors: López, Miguel, Varela, Luis, Vázquez, María J., Rodríguez-Cuenca, Sergio, González, Carmen R., Velagapudi, Vidya R., Morgan, Donald A., Schoenmakers, Erik, Agassandian, Khristofor, Lage, Ricardo, de Morentin, Pablo Blanco Martínez, Tovar, Sulay, Nogueiras, Rubén, Carling, David, Lelliott, Christopher, Gallego, Rosalía, Orešič, Matej, Chatterjee, Krishna, Saha, Asish K., Rahmouni, Kamal, Diéguez, Carlos, Vidal-Puig, Antonio
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935934/
https://ncbi.nlm.nih.gov/pubmed/20802499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2207
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