Olanzapine-Induced Hyperphagia and Weight Gain Associate with Orexigenic Hypothalamic Neuropeptide Signaling without Concomitant AMPK Phosphorylation

The success of antipsychotic drug treatment in patients with schizophrenia is limited by the propensity of these drugs to induce hyperphagia, weight gain and other metabolic disturbances, particularly evident for olanzapine and clozapine. However, the molecular mechanisms involved in antipsychotic-i...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Fernø, Johan, Varela, Luis, Skrede, Silje, Vázquez, María Jesús, Nogueiras, Rubén, Diéguez, Carlos, Vidal-Puig, Antonio, Steen, Vidar M., López, Miguel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113797/
https://ncbi.nlm.nih.gov/pubmed/21695181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020571
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi