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Lack of Ovarian Secretions Reverts the Anabolic Action of Olanzapine in Female Rats

BACKGROUND: Olanzapine is an orexigenic antipsychotic drug associated with serious metabolic adverse effects in humans. Development of valid rodent models for antipsychotic-induced metabolic adverse effects is hampered by the fact that such effects occur in females only. Estradiol is a predominant f...

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Publicado en:Int J Neuropsychopharmacol
Autores principales: Skrede, Silje, González-García, Ismael, Martins, Luís, Berge, Rolf Kristian, Nogueiras, Ruben, Tena-Sempere, Manuel, Mellgren, Gunnar, Steen, Vidar Martin, López, Miguel, Fernø, Johan
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716078/
https://ncbi.nlm.nih.gov/pubmed/29020342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyx073
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