Mitochondria in the diabetic heart

Por Bugger, Heiko, Abel, E. Dale
Publicado em 2010

Molecular mechanisms of diabetic cardiomyopathy

Por Bugger, Heiko, Abel, E. Dale
Publicado em 2014

SIRT3 in Cardiac Physiology and Disease

Por Koentges, Christoph, Bode, Christoph, Bugger, Heiko
Publicado no Front Cardiovasc Med (2016)

Diabetic Cardiomyopathy: Does the Type of Diabetes Matter?

Por Hölscher, Maximilian E., Bode, Christoph, Bugger, Heiko
Publicado no Int J Mol Sci (2016)

Mitochondrial Mechanisms in Septic Cardiomyopathy

Por Cimolai, María Cecilia, Alvarez, Silvia, Bode, Christoph, Bugger, Heiko
Publicado no Int J Mol Sci (2015)

UNCOUPLING PROTEIN DOWNREGULATION IN DOXORUBICIN INDUCED HEART FAILURE IMPROVES MITOCHONDRIAL COUPLING BUT INCREASES REACTIVE OXYGEN SPECIES GENERATION

Por Bugger, Heiko, Guzman, Cinthia, Zechner, Christoph, Palmeri, Monica, Russell, Kerry S., Russell, Raymond R.
Publicado em 2010

Insulin Signaling Regulates Mitochondrial Function in Pancreatic β-Cells

Por Liu, Siming, Okada, Terumasa, Assmann, Anke, Soto, Jamie, Liew, Chong Wee, Bugger, Heiko, Shirihai, Orian S., Abel, E. Dale, Kulkarni, Rohit N.
Publicado em 2009

Central Leptin Signaling Is Required to Normalize Myocardial Fatty Acid Oxidation Rates in Caloric-Restricted ob/ob Mice

Por Sloan, Crystal, Tuinei, Joseph, Nemetz, Katherine, Frandsen, Jonathan, Soto, Jamie, Wride, Noah, Sempokuya, Tomoki, Alegria, Luis, Bugger, Heiko, Abel, E. Dale
Publicado em 2011

Tissue-Specific Remodeling of the Mitochondrial Proteome in Type 1 Diabetic Akita Mice

Por Bugger, Heiko, Chen, Dong, Riehle, Christian, Soto, Jamie, Theobald, Heather A., Hu, Xiao X., Ganesan, Balasubramanian, Weimer, Bart C., Abel, E. Dale
Publicado em 2009

Myocardial Mitochondrial and Contractile Function Are Preserved in Mice Lacking Adiponectin

Por Braun, Martin, Hettinger, Niko, Koentges, Christoph, Pfeil, Katharina, Cimolai, Maria C., Hoffmann, Michael M., Osterholt, Moritz, Doenst, Torsten, Bode, Christoph, Bugger, Heiko
Publicado no PLoS One (2015)

Antioxidant treatment normalizes mitochondrial energetics and myocardial insulin sensitivity independently of changes in systemic metabolic homeostasis in a mouse model of the meta...

Por Ilkun, Olesya, Wilde, Nicole, Tunei, Joseph, Pires, Karla M.P., Zhu, Yi, Bugger, Heiko, Soto, Jamie, Wayment, Benjamin, Olsen, Curtis, Litwin, Sheldon E., Abel, E. Dale
Publicado no J Mol Cell Cardiol (2015)

Type 1 Diabetic Akita Mouse Hearts Are Insulin Sensitive but Manifest Structurally Abnormal Mitochondria That Remain Coupled Despite Increased Uncoupling Protein 3

Por Bugger, Heiko, Boudina, Sihem, Hu, Xiao Xuan, Tuinei, Joseph, Zaha, Vlad G., Theobald, Heather A., Yun, Ui Jeong, McQueen, Alfred P., Wayment, Benjamin, Litwin, Sheldon E., Abel, E. Dale
Publicado em 2008

Mechanistic Target of Rapamycin (Mtor) Is Essential for Murine Embryonic Heart Development and Growth

Por Zhu, Yi, Pires, Karla M. P., Whitehead, Kevin J., Olsen, Curtis D., Wayment, Benjamin, Zhang, Yi Cheng, Bugger, Heiko, Ilkun, Olesya, Litwin, Sheldon E., Thomas, George, Kozma, Sara C., Abel, E. Dale
Publicado em 2013

Genetic Loss of Insulin Receptors Worsens Cardiac Efficiency in Diabetes

Por Bugger, Heiko, Riehle, Christian, Jaishy, Bharat, Wende, Adam R., Tuinei, Joseph, Chen, Dong, Soto, Jamie, Pires, Karla M., Boudina, Sihem, Theobald, Heather A., Luptak, Ivan, Wayment, Benjamin, Wang, Xiaohui, Litwin, Sheldon E., Weimer, Bart C., Abel, E. Dale
Publicado em 2012

PGC-1β Deficiency Accelerates the Transition to Heart Failure in Pressure Overload Hypertrophy: PGC-1β and Pressure Overload

Por Riehle, Christian, Wende, Adam R, Zaha, Vlad G, Pires, Karla Maria, Wayment, Benjamin, Olsen, Curtis, Bugger, Heiko, Buchanan, Jonathan, Wang, Xiaohui, Moreira, Annie Bello, Doenst, Torsten, Medina-Gomez, Gema, Litwin, Sheldon E, Lelliott, Christopher J, Vidal-Puig, Antonio, Abel, E. Dale
Publicado em 2011

Insulin receptor substrate signaling suppresses neonatal autophagy in the heart

Por Riehle, Christian, Wende, Adam R., Sena, Sandra, Pires, Karla Maria, Pereira, Renata Oliveira, Zhu, Yi, Bugger, Heiko, Frank, Deborah, Bevins, Jack, Chen, Dong, Perry, Cynthia N., Dong, Xiaocheng C., Valdez, Steven, Rech, Monika, Sheng, Xiaoming, Weimer, Bart C., Gottlieb, Roberta A., White, Morris F., Abel, E. Dale
Publicado em 2013

CONTRIBUTION OF IMPAIRED MYOCARDIAL INSULIN SIGNALING TO MITOCHONDRIAL DYSFUNCTION AND OXIDATIVE STRESS IN THE HEART

Por Boudina, Sihem, Bugger, Heiko, Sena, Sandra, O’Neill, Brian T., Zaha, Vlad G., Ilkun, Olesya, Wright, Jordan J., Mazumder, Pradip K., Palfreyman, Eric, Tidwell, Timothy J., Theobald, Heather, Khalimonchuk, Oleh, Wayment, Benjamin, Sheng, Xiaoming, Rodnick, Kenneth J., Centini, Ryan, Chen, Dong, Litwin, Sheldon E., Weimer, Bart E., Abel, E. Dale
Publicado em 2009

Enhanced Cardiac Akt/Protein Kinase B Signaling Contributes to Pathological Cardiac Hypertrophy in Part by Impairing Mitochondrial Function via Transcriptional Repression of Mitoch...

Por Wende, Adam R., O'Neill, Brian T., Bugger, Heiko, Riehle, Christian, Tuinei, Joseph, Buchanan, Jonathan, Tsushima, Kensuke, Wang, Li, Caro, Pilar, Guo, Aili, Sloan, Crystal, Kim, Bum Jun, Wang, Xiaohui, Pereira, Renata O., McCrory, Mark A., Nye, Brenna G., Benavides, Gloria A., Darley-Usmar, Victor M., Shioi, Tetsuo, Weimer, Bart C., Abel, E. Dale
Publicado no Mol Cell Biol (2015)

Adrenergic Repression of the Epigenetic Reader MeCP2 Facilitates Cardiac Adaptation in Chronic Heart Failure

Por Mayer, Sandra C., Gilsbach, Ralf, Preissl, Sebastian, Monroy Ordonez, Elsa Beatriz, Schnick, Tilman, Beetz, Nadine, Lother, Achim, Rommel, Carolin, Ihle, Hannah, Bugger, Heiko, Rühle, Frank, Schrepper, Andrea, Schwarzer, Michael, Heilmann, Claudia, Bönisch, Ulrike, Gupta, Shashi Kumar, Wilpert, Jochen, Kretz, Oliver, von Elverfeldt, Dominik, Orth, Joachim, Aktories, Klaus, Beyersdorf, Friedhelm, Bode, Christoph, Stiller, Brigitte, Krüger, Markus, Thum, Thomas, Doenst, Torsten, Stoll, Monika, Hein, Lutz
Publicado no Circ Res (2015)