CONTRIBUTION OF IMPAIRED MYOCARDIAL INSULIN SIGNALING TO MITOCHONDRIAL DYSFUNCTION AND OXIDATIVE STRESS IN THE HEART

BACKGROUND: Diabetes-associated cardiac dysfunction is associated with mitochondrial dysfunction and oxidative stress, which may contribute to LV dysfunction. The contribution of altered myocardial insulin action, independently of associated changes in systemic metabolism is incompletely understood....

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Detalhes bibliográficos
Main Authors: Boudina, Sihem, Bugger, Heiko, Sena, Sandra, O’Neill, Brian T., Zaha, Vlad G., Ilkun, Olesya, Wright, Jordan J., Mazumder, Pradip K., Palfreyman, Eric, Tidwell, Timothy J., Theobald, Heather, Khalimonchuk, Oleh, Wayment, Benjamin, Sheng, Xiaoming, Rodnick, Kenneth J., Centini, Ryan, Chen, Dong, Litwin, Sheldon E., Weimer, Bart E., Abel, E. Dale
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739097/
https://ncbi.nlm.nih.gov/pubmed/19237663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.792101
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