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Antioxidant treatment normalizes mitochondrial energetics and myocardial insulin sensitivity independently of changes in systemic metabolic homeostasis in a mouse model of the metabolic syndrome

Cardiac dysfunction in obesity is associated with mitochondrial dysfunction, oxidative stress and altered insulin sensitivity. Whether oxidative stress directly contributes to myocardial insulin resistance remains to be determined. This study tested the hypothesis that ROS scavenging will improve mi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Mol Cell Cardiol
Egile Nagusiak: Ilkun, Olesya, Wilde, Nicole, Tunei, Joseph, Pires, Karla M.P., Zhu, Yi, Bugger, Heiko, Soto, Jamie, Wayment, Benjamin, Olsen, Curtis, Litwin, Sheldon E., Abel, E. Dale
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530070/
https://ncbi.nlm.nih.gov/pubmed/26004364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.05.012
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