Insulin receptor substrate signaling suppresses neonatal autophagy in the heart

The induction of autophagy in the mammalian heart during the perinatal period is an essential adaptation required to survive early neonatal starvation; however, the mechanisms that mediate autophagy suppression once feeding is established are not known. Insulin signaling in the heart is transduced v...

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Autores principales: Riehle, Christian, Wende, Adam R., Sena, Sandra, Pires, Karla Maria, Pereira, Renata Oliveira, Zhu, Yi, Bugger, Heiko, Frank, Deborah, Bevins, Jack, Chen, Dong, Perry, Cynthia N., Dong, Xiaocheng C., Valdez, Steven, Rech, Monika, Sheng, Xiaoming, Weimer, Bart C., Gottlieb, Roberta A., White, Morris F., Abel, E. Dale
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859408/
https://ncbi.nlm.nih.gov/pubmed/24177427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI71171
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