Insulin Signaling Regulates Mitochondrial Function in Pancreatic β-Cells

Insulin/IGF-I signaling regulates the metabolism of most mammalian tissues including pancreatic islets. To dissect the mechanisms linking insulin signaling with mitochondrial function, we first identified a mitochondria-tethering complex in β-cells that included glucokinase (GK), and the pro-apoptot...

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Detalhes bibliográficos
Main Authors: Liu, Siming, Okada, Terumasa, Assmann, Anke, Soto, Jamie, Liew, Chong Wee, Bugger, Heiko, Shirihai, Orian S., Abel, E. Dale, Kulkarni, Rohit N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776992/
https://ncbi.nlm.nih.gov/pubmed/19956695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007983
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