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Insulin receptors in β-cells are critical for islet compensatory growth response to insulin resistance

Insulin and insulin-like growth factor 1 (IGF1) are ubiquitous growth factors that regulate proliferation in most mammalian tissues including pancreatic islets. To explore the specificity of insulin receptors in compensatory β-cell growth, we examined two models of insulin resistance. In the first m...

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Main Authors: Okada, Terumasa, Liew, Chong Wee, Hu, Jiang, Hinault, Charlotte, Michael, M. Dodson, Kr̈tzfeldt, Jan, Yin, Catherine, Holzenberger, Martin, Stoffel, Markus, Kulkarni, Rohit N.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2007
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885613/
https://ncbi.nlm.nih.gov/pubmed/17416680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608703104
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