Suppression of IGF-I signals in neural stem cells enhances neurogenesis and olfactory function during aging

par Chaker, Zayna, Aïd, Saba, Berry, Hugues, Holzenberger, Martin
Publié dans Aging Cell (2015)

Blocking IGF Signaling in Adult Neurons Alleviates Alzheimer's Disease Pathology through Amyloid-β Clearance

par Gontier, Géraldine, George, Caroline, Chaker, Zayna, Holzenberger, Martin, Aïd, Saba
Publié dans J Neurosci (2015)

Longevity effect of IGF-1R(+/−) mutation depends on genetic background-specific receptor activation

par Xu, Jie, Gontier, Géraldine, Chaker, Zayna, Lacube, Philippe, Dupont, Joëlle, Holzenberger, Martin
Publié dans Aging Cell (2014)

Expression of Dominant-Negative Thyroid Hormone Receptor Alpha1 in Leydig and Sertoli Cells Demonstrates No Additional Defect Compared with Expression in Sertoli Cells Only

par Fumel, Betty, Froment, Pascal, Holzenberger, Martin, Livera, Gabriel, Monget, Philippe, Fouchécourt, Sophie
Publié dans PLoS One (2015)

Selective Expression of Insulin-Like Growth Factor II in the Songbird Brain

par Holzenberger, Martin, Jarvis, Erich D., Chong, Christopher, Grossman, Matthew, Nottebohm, Fernando, Scharff, Constance
Publié dans J Neurosci (1997)

IGF-1R Contributes to Stress-Induced Hepatocellular Damage in Experimental Cholestasis

par Cadoret, Axelle, Rey, Colette, Wendum, Dominique, Elriz, Khaldoun, Tronche, François, Holzenberger, Martin, Housset, Chantal
Publié 2009

Proinflammatory Actions of Visfatin/Nicotinamide Phosphoribosyltransferase (Nampt) Involve Regulation of Insulin Signaling Pathway and Nampt Enzymatic Activity

par Jacques, Claire, Holzenberger, Martin, Mladenovic, Zvezdana, Salvat, Colette, Pecchi, Emilie, Berenbaum, Francis, Gosset, Marjolaine
Publié 2012

Cre-mediated germline mosaicism: a method allowing rapid generation of several alleles of a target gene

par Holzenberger, Martin, Lenzner, Claudia, Leneuve, Patricia, Zaoui, Randa, Hamard, Ghislaine, Vaulont, Sophie, Le Bouc, Yves
Publié 2000

Cre-mediated germline mosaicism: a new transgenic mouse for the selective removal of residual markers from tri-lox conditional alleles

par Leneuve, Patricia, Colnot, Sabine, Hamard, Ghislaine, Francis, Fiona, Niwa-Kawakita, Michiko, Giovannini, Marco, Holzenberger, Martin
Publié 2003

Knockout of insulin and IGF-1 receptors on vascular endothelial cells protects against retinal neovascularization

par Kondo, Tatsuya, Vicent, David, Suzuma, Kiyoshi, Yanagisawa, Masashi, King, George L., Holzenberger, Martin, Kahn, C. Ronald
Publié 2003

IGF-IR determines the fates of BCR/ABL leukemia

par Xie, Jingjing, Chen, Xiaoli, Zheng, Junke, Li, Chunling, Stacy, Satomi, Holzenberger, Martin, Hu, Xuemei, Zhang, Cheng Cheng
Publié dans J Hematol Oncol (2015)

Deficiency in type 1 insulin-like growth factor receptor in mice protects against oxygen-induced lung injury

par Ahamed, Karmene, Epaud, Ralph, Holzenberger, Martin, Bonora, Monique, Flejou, Jean-François, Puard, Julien, Clement, Annick, Henrion-Caude, Alexandra
Publié 2005

Insulin-Like Growth Factor 1 Receptor Signaling Regulates Skin Development and Inhibits Skin Keratinocyte Differentiation

par Sadagurski, Marianna, Yakar, Shoshana, Weingarten, Galina, Holzenberger, Martin, Rhodes, Christopher J., Breitkreutz, Dirk, LeRoith, Derek, Wertheimer, Efrat
Publié 2006

Essential Role of Insulin and Insulin-Like Growth Factor 1 Receptor Signaling in Cardiac Development and Function

par Laustsen, Palle G., Russell, Steven J., Cui, Lei, Entingh-Pearsall, Amelia, Holzenberger, Martin, Liao, Ronglih, Kahn, C. Ronald
Publié 2007

IGF binding protein 2 supports the survival and cycling of hematopoietic stem cells

par Huynh, HoangDinh, Zheng, Junke, Umikawa, Masato, Zhang, Chaozheng, Silvany, Robert, Iizuka, Satoru, Holzenberger, Martin, Zhang, Wei, Zhang, Cheng Cheng
Publié 2011

Components of the Hematopoietic Compartments in Tumor Stroma and Tumor-Bearing Mice

par Huynh, HoangDinh, Zheng, Junke, Umikawa, Masato, Silvany, Robert, Xie, Xian-Jin, Wu, Catherine J., Holzenberger, Martin, Wang, Qianming, Zhang, Cheng Cheng
Publié 2011

Interaction of myocardial insulin receptor and IGF receptor signaling in exercise-induced cardiac hypertrophy

par Ikeda, Hiroyuki, Shiojima, Ichiro, Ozasa, Yukako, Yoshida, Masashi, Holzenberger, Martin, Kahn, C Ronald, Walsh, Kenneth, Igarashi, Takashi, Abel, E Dale, Komuro, Issei
Publié dans J Mol Cell Cardiol (2009)

Insulin receptors in β-cells are critical for islet compensatory growth response to insulin resistance

par Okada, Terumasa, Liew, Chong Wee, Hu, Jiang, Hinault, Charlotte, Michael, M. Dodson, Kr̈tzfeldt, Jan, Yin, Catherine, Holzenberger, Martin, Stoffel, Markus, Kulkarni, Rohit N.
Publié 2007

Insulin-like growth factor 1 receptor regulates hypothermia during calorie restriction

par Cintron-Colon, Rigo, Sanchez-Alavez, Manuel, Nguyen, William, Mori, Simone, Gonzalez-Rivera, Ruben, Lien, Tiffany, Bartfai, Tamas, Aïd, Saba, François, Jean-Christophe, Holzenberger, Martin, Conti, Bruno
Publié dans Proc Natl Acad Sci U S A (2017)

Brain IGF-1 Receptors Control Mammalian Growth and Lifespan through a Neuroendocrine Mechanism

par Kappeler, Laurent, Filho, Carlos De Magalhaes, Dupont, Joëlle, Leneuve, Patricia, Cervera, Pascale, Périn, Laurence, Loudes, Catherine, Blaise, Annick, Klein, Rüdiger, Epelbaum, Jacques, Bouc, Yves Le, Holzenberger, Martin
Publié 2008