IGF-IR determines the fates of BCR/ABL leukemia

BACKGROUND: The tyrosine kinase receptor insulin-like growth factor 1 receptor (IGF-IR) contributes to the initiation and progression of many types of malignancies. We previously showed that IGF-2, which binds IGF-IR, is an extrinsic factor that supports the ex vivo expansion of hematopoietic stem c...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Xie, Jingjing, Chen, Xiaoli, Zheng, Junke, Li, Chunling, Stacy, Satomi, Holzenberger, Martin, Hu, Xuemei, Zhang, Cheng Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320836/
https://ncbi.nlm.nih.gov/pubmed/25648584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-015-0106-8
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