Pharmacogenetics of BCR/ABL Inhibitors in Chronic Myeloid Leukemia

Chronic myeloid leukemia was the first haematological neoplasia that benefited from a targeted therapy with imatinib nearly 15 years ago. Since then, several studies have investigated the role of genes, their variants (i.e., polymorphisms) and their encoded proteins in the pharmacokinetics and pharm...

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Udgivet i:Int J Mol Sci
Main Authors: Polillo, Marialuisa, Galimberti, Sara, Baratè, Claudia, Petrini, Mario, Danesi, Romano, Di Paolo, Antonello
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2015
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613337/
https://ncbi.nlm.nih.gov/pubmed/26402671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160922811
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