Concise Review: Chronic Myeloid Leukemia: Stem Cell Niche and Response to Pharmacologic Treatment

Nowadays, more than 90% of patients affected by chronic myeloid leukemia (CML) survive with a good quality of life, thanks to the clinical efficacy of tyrosine kinase inhibitors (TKIs). Nevertheless, point mutations of the ABL1 pocket occurring during treatment may reduce binding of TKIs, being resp...

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Main Authors: Arrigoni, Elena, Del Re, Marzia, Galimberti, Sara, Restante, Giuliana, Rofi, Eleonora, Crucitta, Stefania, Baratè, Claudia, Petrini, Mario, Danesi, Romano, Di Paolo, Antonello
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Translational Research Articles and Reviews
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827745/
https://ncbi.nlm.nih.gov/pubmed/29418079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.17-0175
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