Concise Review: Chronic Myeloid Leukemia: Stem Cell Niche and Response to Pharmacologic Treatment

Nowadays, more than 90% of patients affected by chronic myeloid leukemia (CML) survive with a good quality of life, thanks to the clinical efficacy of tyrosine kinase inhibitors (TKIs). Nevertheless, point mutations of the ABL1 pocket occurring during treatment may reduce binding of TKIs, being resp...

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Bibliografiska uppgifter
I publikationen:Stem Cells Transl Med
Huvudupphovsmän: Arrigoni, Elena, Del Re, Marzia, Galimberti, Sara, Restante, Giuliana, Rofi, Eleonora, Crucitta, Stefania, Baratè, Claudia, Petrini, Mario, Danesi, Romano, Di Paolo, Antonello
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2018
Ämnen:
Translational Research Articles and Reviews
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827745/
https://ncbi.nlm.nih.gov/pubmed/29418079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.17-0175
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