Concise Review: Chronic Myeloid Leukemia: Stem Cell Niche and Response to Pharmacologic Treatment

Nowadays, more than 90% of patients affected by chronic myeloid leukemia (CML) survive with a good quality of life, thanks to the clinical efficacy of tyrosine kinase inhibitors (TKIs). Nevertheless, point mutations of the ABL1 pocket occurring during treatment may reduce binding of TKIs, being resp...

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Foilsithe in:Stem Cells Transl Med
Main Authors: Arrigoni, Elena, Del Re, Marzia, Galimberti, Sara, Restante, Giuliana, Rofi, Eleonora, Crucitta, Stefania, Baratè, Claudia, Petrini, Mario, Danesi, Romano, Di Paolo, Antonello
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2018
Ábhair:
Translational Research Articles and Reviews
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827745/
https://ncbi.nlm.nih.gov/pubmed/29418079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.17-0175
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