PD-L1 mRNA expression in plasma-derived exosomes is associated with response to anti-PD-1 antibodies in melanoma and NSCLC

BACKGROUND: PD-L1 expression in tumour tissues is widely used to select patients to receive anti-PD-1/PD-L1 antibodies, but data are lacking on the correlation of plasma PD-L1 levels with the effect of treatments. METHODS: To investigate the association between PD-L1 mRNA in plasma-derived exosomes...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Del Re, Marzia, Marconcini, Riccardo, Pasquini, Giulia, Rofi, Eleonora, Vivaldi, Caterina, Bloise, Francesco, Restante, Giuliana, Arrigoni, Elena, Caparello, Chiara, Bianco, Maria Grazia, Crucitta, Stefania, Petrini, Iacopo, Vasile, Enrico, Falcone, Alfredo, Danesi, Romano
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886129/
https://ncbi.nlm.nih.gov/pubmed/29509748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2018.9
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