PD-L1 mRNA expression in plasma-derived exosomes is associated with response to anti-PD-1 antibodies in melanoma and NSCLC

BACKGROUND: PD-L1 expression in tumour tissues is widely used to select patients to receive anti-PD-1/PD-L1 antibodies, but data are lacking on the correlation of plasma PD-L1 levels with the effect of treatments. METHODS: To investigate the association between PD-L1 mRNA in plasma-derived exosomes...

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Dades bibliogràfiques
Publicat a:Br J Cancer
Autors principals: Del Re, Marzia, Marconcini, Riccardo, Pasquini, Giulia, Rofi, Eleonora, Vivaldi, Caterina, Bloise, Francesco, Restante, Giuliana, Arrigoni, Elena, Caparello, Chiara, Bianco, Maria Grazia, Crucitta, Stefania, Petrini, Iacopo, Vasile, Enrico, Falcone, Alfredo, Danesi, Romano
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2018
Matèries:
Translational Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886129/
https://ncbi.nlm.nih.gov/pubmed/29509748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2018.9
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