PD-L1 mRNA expression in plasma-derived exosomes is associated with response to anti-PD-1 antibodies in melanoma and NSCLC

BACKGROUND: PD-L1 expression in tumour tissues is widely used to select patients to receive anti-PD-1/PD-L1 antibodies, but data are lacking on the correlation of plasma PD-L1 levels with the effect of treatments. METHODS: To investigate the association between PD-L1 mRNA in plasma-derived exosomes...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Br J Cancer
Autori principali: Del Re, Marzia, Marconcini, Riccardo, Pasquini, Giulia, Rofi, Eleonora, Vivaldi, Caterina, Bloise, Francesco, Restante, Giuliana, Arrigoni, Elena, Caparello, Chiara, Bianco, Maria Grazia, Crucitta, Stefania, Petrini, Iacopo, Vasile, Enrico, Falcone, Alfredo, Danesi, Romano
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2018
Soggetti:
Translational Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886129/
https://ncbi.nlm.nih.gov/pubmed/29509748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2018.9
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