Concise Review: Chronic Myeloid Leukemia: Stem Cell Niche and Response to Pharmacologic Treatment

Nowadays, more than 90% of patients affected by chronic myeloid leukemia (CML) survive with a good quality of life, thanks to the clinical efficacy of tyrosine kinase inhibitors (TKIs). Nevertheless, point mutations of the ABL1 pocket occurring during treatment may reduce binding of TKIs, being resp...

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Detaylı Bibliyografya
Yayımlandı:Stem Cells Transl Med
Asıl Yazarlar: Arrigoni, Elena, Del Re, Marzia, Galimberti, Sara, Restante, Giuliana, Rofi, Eleonora, Crucitta, Stefania, Baratè, Claudia, Petrini, Mario, Danesi, Romano, Di Paolo, Antonello
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2018
Konular:
Translational Research Articles and Reviews
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827745/
https://ncbi.nlm.nih.gov/pubmed/29418079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.17-0175
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