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Knockout of insulin and IGF-1 receptors on vascular endothelial cells protects against retinal neovascularization
Both insulin and IGF-1 have been implicated in control of retinal endothelial cell growth, neovascularization, and diabetic retinopathy. To precisely define the role of insulin and IGF-1 signaling in endothelium in these processes, we have used the oxygen-induced retinopathy model to study mice with...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC161423/ https://ncbi.nlm.nih.gov/pubmed/12813019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317455 |
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