SALL4 controls cell fate in response to DNA base composition

Mammalian genomes contain long domains with distinct average compositions of A/T versus G/C base pairs. In a screen for proteins that might interpret base composition by binding to AT-rich motifs, we identified the stem cell factor SALL4, which contains multiple zinc fingers. Mutation of the domain...

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Foilsithe in:Mol Cell
Main Authors: Pantier, Raphaël, Chhatbar, Kashyap, Quante, Timo, Skourti-Stathaki, Konstantina, Cholewa-Waclaw, Justyna, Alston, Grace, Alexander-Howden, Beatrice, Lee, Heng Yang, Cook, Atlanta G., Spruijt, Cornelia G., Vermeulen, Michiel, Selfridge, Jim, Bird, Adrian
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cell Press 2021
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7895904/
https://ncbi.nlm.nih.gov/pubmed/33406384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.11.046
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