An Orphan CpG Island Drives Expression of a let-7 miRNA Precursor with an Important Role in Mouse Development

Most human genes are associated with promoters embedded in non-methylated, G + C-rich CpG islands (CGIs). Not all CGIs are found at annotated promoters, however, raising the possibility that many serve as promoters for transcripts that do not code for proteins. To test this hypothesis, we searched f...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Epigenomes
Autori principali: Koerner, Martha V., Chhatbar, Kashyap, Webb, Shaun, Cholewa-Waclaw, Justyna, Selfridge, Jim, De Sousa, Dina, Skarnes, Bill, Rosen, Barry, Thomas, Mark, Bottomley, Joanna, Ramirez-Solis, Ramiro, Lelliott, Christopher, Adams, David J., Bird, Adrian
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660310/
https://ncbi.nlm.nih.gov/pubmed/31354981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/epigenomes3010007
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi