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Orphan CpG islands as alternative promoters

CpG islands (CGIs) are associated with ∼60% of mammalian promoters. Most unmethylated CGIs exhibit transcriptional activity, which has led to their co-option as promoters by retrogenes. CGIs may also serve as alternative promoters for downstream genes with methylated promoters, with implications on...

詳細記述

保存先:
書誌詳細
出版年:Transcription
主要な著者: Sarda, Shrutii, Hannenhalli, Sridhar
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927659/
https://ncbi.nlm.nih.gov/pubmed/29099304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541264.2017.1373209
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