Orphan CpG Islands Identify Numerous Conserved Promoters in the Mammalian Genome

CpG islands (CGIs) are vertebrate genomic landmarks that encompass the promoters of most genes and often lack DNA methylation. Querying their apparent importance, the number of CGIs is reported to vary widely in different species and many do not co-localise with annotated promoters. We set out to qu...

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Αποθηκεύτηκε σε:
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Κύριοι συγγραφείς: Illingworth, Robert S., Gruenewald-Schneider, Ulrike, Webb, Shaun, Kerr, Alastair R. W., James, Keith D., Turner, Daniel J., Smith, Colin, Harrison, David J., Andrews, Robert, Bird, Adrian P.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2010
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944787/
https://ncbi.nlm.nih.gov/pubmed/20885785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001134
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