Orphan CpG Islands Identify Numerous Conserved Promoters in the Mammalian Genome

CpG islands (CGIs) are vertebrate genomic landmarks that encompass the promoters of most genes and often lack DNA methylation. Querying their apparent importance, the number of CGIs is reported to vary widely in different species and many do not co-localise with annotated promoters. We set out to qu...

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Detalhes bibliográficos
Main Authors: Illingworth, Robert S., Gruenewald-Schneider, Ulrike, Webb, Shaun, Kerr, Alastair R. W., James, Keith D., Turner, Daniel J., Smith, Colin, Harrison, David J., Andrews, Robert, Bird, Adrian P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944787/
https://ncbi.nlm.nih.gov/pubmed/20885785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001134
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