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Initiation of DNA replication at CpG islands in mammalian chromosomes.

CpG islands are G+C-rich regions approximately 1 kb long that are free of methylation and contain the promoters of many mammalian genes. Analysis of in vivo replication intermediates at three hamster genes and one human gene showed that the CpG island regions, but not their flanks, were present in v...

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Détails bibliographiques
Auteurs principaux: Delgado, S, Gómez, M, Bird, A, Antequera, F
Format: Artigo
Langue:Inglês
Publié: 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170585/
https://ncbi.nlm.nih.gov/pubmed/9545253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.8.2426
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