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Initiation of DNA replication at CpG islands in mammalian chromosomes.

CpG islands are G+C-rich regions approximately 1 kb long that are free of methylation and contain the promoters of many mammalian genes. Analysis of in vivo replication intermediates at three hamster genes and one human gene showed that the CpG island regions, but not their flanks, were present in v...

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Bibliografiske detaljer
Main Authors: Delgado, S, Gómez, M, Bird, A, Antequera, F
Format: Artigo
Sprog:Inglês
Udgivet: 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170585/
https://ncbi.nlm.nih.gov/pubmed/9545253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.8.2426
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