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CpG islands and the regulation of transcription

Vertebrate CpG islands (CGIs) are short interspersed DNA sequences that deviate significantly from the average genomic pattern by being GC-rich, CpG-rich, and predominantly nonmethylated. Most, perhaps all, CGIs are sites of transcription initiation, including thousands that are remote from currentl...

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Bibliographic Details
Main Authors: Deaton, Aimée M., Bird, Adrian
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093116/
https://ncbi.nlm.nih.gov/pubmed/21576262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2037511
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