Orphan CpG Islands Identify Numerous Conserved Promoters in the Mammalian Genome

CpG islands (CGIs) are vertebrate genomic landmarks that encompass the promoters of most genes and often lack DNA methylation. Querying their apparent importance, the number of CGIs is reported to vary widely in different species and many do not co-localise with annotated promoters. We set out to qu...

Full description

Saved in:
Bibliographic Details
Main Authors: Illingworth, Robert S., Gruenewald-Schneider, Ulrike, Webb, Shaun, Kerr, Alastair R. W., James, Keith D., Turner, Daniel J., Smith, Colin, Harrison, David J., Andrews, Robert, Bird, Adrian P.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944787/
https://ncbi.nlm.nih.gov/pubmed/20885785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001134
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items