A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog

The histone deacetylases HDAC1 and HDAC2 are crucial regulators of chromatin structure and gene expression, thereby controlling important developmental processes. In the mouse brain, HDAC1 and HDAC2 exhibit different developmental stage- and lineage-specific expression patterns. To examine the indiv...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Hagelkruys, Astrid, Lagger, Sabine, Krahmer, Julia, Leopoldi, Alexandra, Artaker, Matthias, Pusch, Oliver, Zezula, Jürgen, Weissmann, Simon, Xie, Yunli, Schöfer, Christian, Schlederer, Michaela, Brosch, Gerald, Matthias, Patrick, Selfridge, Jim, Lassmann, Hans, Knoblich, Jürgen A., Seiser, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773893/
https://ncbi.nlm.nih.gov/pubmed/24449838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.100487
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