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Distinct and redundant functions of histone deacetylases HDAC1 and HDAC2 in proliferation and tumorigenesis

Histone deacetylases (HDACs) are negative regulators of gene expression and have been implicated in tumorigenesis and tumor progression. Therefore, HDACs are promising targets for antitumor drugs. However, the relevant isoforms of the 18 members encompassing HDAC family have not been identified. Stu...

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Detalhes bibliográficos
Main Authors: Jurkin, Jennifer, Zupkovitz, Gordin, Lagger, Sabine, Grausenburger, Reinhard, Hagelkruys, Astrid, Kenner, Lukas, Seiser, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115015/
https://ncbi.nlm.nih.gov/pubmed/21270520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.3.14712
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