Distinct and redundant functions of histone deacetylases HDAC1 and HDAC2 in proliferation and tumorigenesis

Histone deacetylases (HDACs) are negative regulators of gene expression and have been implicated in tumorigenesis and tumor progression. Therefore, HDACs are promising targets for antitumor drugs. However, the relevant isoforms of the 18 members encompassing HDAC family have not been identified. Stu...

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Main Authors: Jurkin, Jennifer, Zupkovitz, Gordin, Lagger, Sabine, Grausenburger, Reinhard, Hagelkruys, Astrid, Kenner, Lukas, Seiser, Christian
格式: Artigo
語言:Inglês
出版: Landes Bioscience 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115015/
https://ncbi.nlm.nih.gov/pubmed/21270520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.3.14712
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