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Distinct and redundant functions of histone deacetylases HDAC1 and HDAC2 in proliferation and tumorigenesis
Histone deacetylases (HDACs) are negative regulators of gene expression and have been implicated in tumorigenesis and tumor progression. Therefore, HDACs are promising targets for antitumor drugs. However, the relevant isoforms of the 18 members encompassing HDAC family have not been identified. Stu...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Landes Bioscience
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3115015/ https://ncbi.nlm.nih.gov/pubmed/21270520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.3.14712 |
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