The Cyclin-Dependent Kinase Inhibitor p21 Is a Crucial Target for Histone Deacetylase 1 as a Regulator of Cellular Proliferation

Histone deacetylases (HDACs) are chromatin-modifying enzymes that are involved in the regulation of proliferation, differentiation and development. HDAC inhibitors induce cell cycle arrest, differentiation, or apoptosis in tumor cells and are therefore promising antitumor agents. Numerous genes were...

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Detalhes bibliográficos
Main Authors: Zupkovitz, Gordin, Grausenburger, Reinhard, Brunmeir, Reinhard, Senese, Silvia, Tischler, Julia, Jurkin, Jennifer, Rembold, Martina, Meunier, Dominique, Egger, Gerda, Lagger, Sabine, Chiocca, Susanna, Propst, Fritz, Weitzer, Georg, Seiser, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820891/
https://ncbi.nlm.nih.gov/pubmed/20028735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01500-09
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