Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression

Histone deacetylases (HDACs) modulate chromatin structure and transcription, but little is known about their function in mammalian development. HDAC1 was implicated previously in the repression of genes required for cell proliferation and differentiation. Here we show that targeted disruption of bot...

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Detalles Bibliográficos

Publicado en:	EMBO J
Principais autores:	Lagger, Gerda, O’Carroll, Dónal, Rembold, Martina, Khier, Harald, Tischler, Julia, Weitzer, Georg, Schuettengruber, Bernd, Hauser, Christoph, Brunmeir, Reinhard, Jenuwein, Thomas, Seiser, Christian
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Publishing Group 2002
Assuntos:	Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126040/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12032080/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.11.2672
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