Glucocorticoid Receptor Recruitment of Histone Deacetylase 2 Inhibits Interleukin-1β-Induced Histone H4 Acetylation on Lysines 8 and 12

We have investigated the ability of dexamethasone to regulate interleukin-1β (IL-1β)-induced gene expression, histone acetyltransferase (HAT) and histone deacetylase (HDAC) activity. Low concentrations of dexamethasone (10(−10) M) repress IL-1β-stimulated granulocyte-macrophage colony-stimulating fa...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Ito, Kazuhiro, Barnes, Peter J., Adcock, Ian M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC88765/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10958685/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.18.6891-6903.2000
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