The Tumor Suppressor p53 and Histone Deacetylase 1 Are Antagonistic Regulators of the Cyclin-Dependent Kinase Inhibitor p21/WAF1/CIP1 Gene

The cyclin-dependent kinase inhibitor p21/WAF1/CIP1 is an important regulator of cell cycle progression, senescence, and differentiation. Genotoxic stress leads to activation of the tumor suppressor p53 and subsequently to induction of p21 expression. Here we show that the tumor suppressor p53 coope...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Lagger, Gerda, Doetzlhofer, Angelika, Schuettengruber, Bernd, Haidweger, Eva, Simboeck, Elisabeth, Tischler, Julia, Chiocca, Susanna, Suske, Guntram, Rotheneder, Hans, Wintersberger, Erhard, Seiser, Christian
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Transcriptional Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC152549/
https://ncbi.nlm.nih.gov/pubmed/12665570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.8.2669-2679.2003
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares