QR Code

The Tumor Suppressor p53 and Histone Deacetylase 1 Are Antagonistic Regulators of the Cyclin-Dependent Kinase Inhibitor p21/WAF1/CIP1 Gene

The cyclin-dependent kinase inhibitor p21/WAF1/CIP1 is an important regulator of cell cycle progression, senescence, and differentiation. Genotoxic stress leads to activation of the tumor suppressor p53 and subsequently to induction of p21 expression. Here we show that the tumor suppressor p53 coope...

Full description

Saved in:
Published in:Mol Cell Biol
Main Authors: Lagger, Gerda, Doetzlhofer, Angelika, Schuettengruber, Bernd, Haidweger, Eva, Simboeck, Elisabeth, Tischler, Julia, Chiocca, Susanna, Suske, Guntram, Rotheneder, Hans, Wintersberger, Erhard, Seiser, Christian
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2003
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152549/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12665570/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.8.2669-2679.2003
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items